HCID 57440193、化合物 → tert-Butyl {(3S)-4-amino-3-[(tert-butoxycarbonyl)amino]butyl}carbamate

HRID 269619ノート

反応式

HRID 269619 の反応式
[C:1]([O:5][C:6](=[O:23])[NH:7][CH2:8][CH2:9][C@H:10]([NH:15][C:16]([O:18][C:19]([CH3:22])([CH3:21])[CH3:20])=[O:17])[CH2:11][N:12]=[N+]=[N-])([CH3:4])([CH3:3])[CH3:2]>C(O)C.[Pd]>[C:1]([O:5][C:6](=[O:23])[NH:7][CH2:8][CH2:9][C@H:10]([NH:15][C:16]([O:18][C:19]([CH3:22])([CH3:21])[CH3:20])=[O:17])[CH2:11][NH2:12])([CH3:4])([CH3:3])[CH3:2]

参加物

4

反応物 1

HCID 57440193HCID 57440193、化合物

生成物 1

HCID 57440194tert-Butyl {(3S)-4-amino-3-[(tert-butoxycarbonyl)amino]butyl}carbamate

試薬・触媒・溶媒 2

HCID 23938Palladium触媒HCID 702Ethanol溶媒

実験手順

Preparation takes place in analogy to Example 86A from 171 mg (0.52 mmol) of tert-butyl{(3S)-4-azido-3-[(tert-butoxycarbonyl)amino]butyl}carbamate (Example 91A) in 10 ml of ethanol with the addition of 20 mg of palladium on activated carbon (10%). The product is reacted without further purification.

後処理

  1. customPreparation
  2. customThe product is reacted without further purification

出典と根拠

ORDレコード
ord-96eaa377cfe14e8fbcce41788b1fd7dd
出典データセット
uspto-grants-2008_11
特許番号
US07446102B2

反応ノート

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