Hydrochloric Acid → HCID 68746238、化合物

HRID 270237

反応式

HRID 270237 の反応式
[Cl:1][C:2]1[CH:7]=[C:6]([Cl:8])[CH:5]=[CH:4][C:3]=1[CH2:9][C:10]([OH:12])=[O:11].[Mg+2:13].[Cl-:14].[Cl-].Cl.C(N(CC)CC)C>CCCCCCC>[Cl:1][C:2]1[CH:7]=[C:6]([Cl:8])[CH:5]=[CH:4][C:3]=1[CH2:9][C:10]([O-:12])=[O:11].[Cl-:14].[Mg+2:13]

参加物

6

反応物 4

HCID 313Hydrochloric AcidHCID 8471TriethylamineHCID 882092,4-Dichlorophenylacetic acidHCID 5360315Magnesium Chloride

生成物 1

HCID 68746238HCID 68746238、化合物収率 96%

試薬・触媒・溶媒 1

HCID 8900Heptane溶媒

実験手順

215 grams (1.05 moles) of 2,4-dichloro-phenylacetic acid are added to 95.2 grams (1 mole) of MgCl2 suspended in 2 liters of heptane. The suspension is brought to reflux temperature under a light stream of nitrogen and is maintained at boiling point until the complete development of HCl (8-12 hours). After cooling, the reaction mixture is treated with 10.1 g (0.1 moles) of triethylamine and filtered. 253.2 g (96% yield) of white solid are obtained from the filtrate, after evaporation and subsequent drying, with the following elemental analysis:

後処理

  1. temperatureto reflux temperature under a light stream of nitrogen
  2. temperatureis maintained
  3. temperatureAfter cooling
  4. filtrationfiltered

出典と根拠

ORDレコード
ord-1c026f42ce704c3cb65b941af403b5b6
出典データセット
uspto-grants-2008_11
特許番号
US07449528B2

関連ノート

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