Hydrochloric Acid → HCID 22314064、化合物

HRID 270262

反応式

HRID 270262 の反応式
BrCCCCOC1C=CC2C(C3C=CC(Br)=CC=3)=NSC=2C=1.COCCNCC.[Br:30][C:31]1[CH:36]=[CH:35][C:34]([C:37]2[C:41]3[CH:42]=[CH:43][C:44]([O:46][CH2:47][CH2:48][CH2:49][CH2:50][N:51]([CH2:56][CH3:57])[CH2:52][CH2:53][O:54][CH3:55])=[CH:45][C:40]=3[S:39][N:38]=2)=[CH:33][CH:32]=1.[ClH:58]>CO>[ClH:58].[Br:30][C:31]1[CH:32]=[CH:33][C:34]([C:37]2[C:41]3[CH:42]=[CH:43][C:44]([O:46][CH2:47][CH2:48][CH2:49][CH2:50][N:51]([CH2:56][CH3:57])[CH2:52][CH2:53][O:54][CH3:55])=[CH:45][C:40]=3[S:39][N:38]=2)=[CH:35][CH:36]=1

参加物

6

反応物 4

HCID 313Hydrochloric Acid2 回HCID 546877N-(2-Methoxyethyl)ethylamineHCID 22313931HCID 22313931、化合物HCID 22314065HCID 22314065、化合物

生成物 1

HCID 22314064HCID 22314064、化合物

試薬・触媒・溶媒 1

HCID 887Methanol溶媒

実験手順

In analogy to example 3.1, 6-(4-Bromo-butoxy)-3-(4-bromo-phenyl)-benzo[d]isothiazole and N-(2-Methoxyethyl)ethylamine were converted to {4-[3-(4-Bromo-phenyl)-benzo[d]isothiazol-6-yloxy]-butyl}-ethyl-(2-methoxy-ethyl)-amine which was converted to the hydrochloride by treatment with HCl in methanol to yield {4-[3-(4-Bromo-phenyl)-benzo[d]isothiazol-6-yloxy]-butyl}-ethyl-(2-methoxy-ethyl)-amine hydrochloride as light yellow oil, MS: 463(MH+, 1Br).

出典と根拠

ORDレコード
ord-349c7ea7eb594fed8e4695d0d8cc7c61
出典データセット
uspto-grants-2008_11
特許番号
US07449483B2

関連ノート

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