Thionyl Chloride → 2,2-Dichloro-1-(4-ethoxyphenyl)cyclopropane-1-carbonyl chloride

HRID 27049ノート

反応式

HRID 27049 の反応式
[CH2:1]([O:3][C:4]1[CH:9]=[CH:8][C:7]([C:10]2([C:15]([OH:17])=O)[CH2:12][C:11]2([Cl:14])[Cl:13])=[CH:6][CH:5]=1)[CH3:2].S(Cl)([Cl:20])=O>>[CH2:1]([O:3][C:4]1[CH:9]=[CH:8][C:7]([C:10]2([C:15]([Cl:20])=[O:17])[CH2:12][C:11]2([Cl:14])[Cl:13])=[CH:6][CH:5]=1)[CH3:2]

参加物

3

反応物 2

HCID 24386Thionyl ChlorideHCID 135804022,2-Dichloro-1-(4-ethoxyphenyl)cyclopropane-1-carboxylic acid

生成物 1

HCID 130410812,2-Dichloro-1-(4-ethoxyphenyl)cyclopropane-1-carbonyl chloride

実験手順

The 1-p-ethoxyphenyl-2,2-dichlorocyclopropane-1-carboxylic acid (1.38 g) was refluxed on a water bath with thionyl chloride (1.19 g) for 15 minutes. The excess thionyl chloride was then evaporated under vacuum (1 Torr.) and the residue of carbonyl chloride reacted without further purification with one of the alcohols (a), (b), (c) or (d). ##STR11##

後処理

  1. customThe excess thionyl chloride was then evaporated under vacuum (1 Torr.)
  2. customthe residue of carbonyl chloride reacted without further purification with one of the alcohols (a), (b), (c) or (d)

出典と根拠

ORDレコード
ord-75f508af836148c784e52da5e9963009
出典データセット
uspto-grants-1980_09
特許番号
US04220591

反応ノート

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