Hydrazine → HCID 22353179、化合物
反応式
C([O:3][C:4](=O)[CH2:5][C:6](=O)[C:7]1[CH:12]=[C:11]([O:13][CH3:14])[C:10]([O:15][CH3:16])=[C:9]([O:17][CH3:18])[CH:8]=1)C.[NH2:21][NH2:22]>C(#N)C>[CH3:18][O:17][C:9]1[CH:8]=[C:7]([C:6]2[CH2:5][C:4](=[O:3])[NH:21][N:22]=2)[CH:12]=[C:11]([O:13][CH3:14])[C:10]=1[O:15][CH3:16]参加物
4
実験手順
To a stirred solution of 3-oxo-3-(3,4,5-trimethoxyphenyl)-propionic acid ethyl ester (2.82 g, 10 mmol) in dry acetonitrile (15 mL) was added to anhydrous hydrazine (640 mL, 20 mmol) at room temperature. After 1 hour, the mixture was heated to reflux for 16 hours. The mixture was diluted with acetonitrile (20 mL) and the solid was filtered. The solid was washed with acetonitrile (10 mL) and dried under nitrogen to afford 2.2 g of title compound (k).
後処理
- temperaturethe mixture was heated
- temperatureto reflux for 16 hours
- filtrationthe solid was filtered
- washThe solid was washed with acetonitrile (10 mL)
- customdried under nitrogen
出典と根拠
- ORDレコード
- ord-c7d9bdb79795433886ab3fe7521e992a
- 出典データセット
- uspto-grants-2008_11
- 特許番号
- US07452873B2
反応ノート
読み込み中…