Hydrochloric Acid → 3,3,3-Tris(4-vinylphenyl)propionic acid

HRID 272084ノート

反応式

HRID 272084 の反応式
[CH:1]([C:3]1[CH:8]=[CH:7][C:6]([C:9]([C:23]2[CH:28]=[CH:27][C:26]([CH:29]=[CH2:30])=[CH:25][CH:24]=2)([C:15]2[CH:20]=[CH:19][C:18]([CH:21]=[CH2:22])=[CH:17][CH:16]=2)[CH2:10][C:11]([O:13]C)=[O:12])=[CH:5][CH:4]=1)=[CH2:2].[OH-].[Li+].Cl>O1CCOCC1>[CH:29]([C:26]1[CH:25]=[CH:24][C:23]([C:9]([C:6]2[CH:5]=[CH:4][C:3]([CH:1]=[CH2:2])=[CH:8][CH:7]=2)([C:15]2[CH:20]=[CH:19][C:18]([CH:21]=[CH2:22])=[CH:17][CH:16]=2)[CH2:10][C:11]([OH:13])=[O:12])=[CH:28][CH:27]=1)=[CH2:30]

参加物

5

反応物 3

HCID 313Hydrochloric AcidHCID 3939Lithium HydroxideHCID 22647215Methyl 3,3,3-tris(4-vinylphenyl)propionate

生成物 1

HCID 226473893,3,3-Tris(4-vinylphenyl)propionic acid

試薬・触媒・溶媒 1

HCID 312751,4-Dioxane溶媒

反応条件

温度
90 °C

実験手順

Fifty-four (54) mg of methyl 3,3,3-tris(4-vinylphenyl)-propionate was suspended in 0.5 ml of dioxane, and to the suspension 0.5 ml of 4N aqueous lithium hydroxide solution was added at room temperature, followed by 17 hours' stirring at 90° C. under heating. The reaction liquid was made acidic by addition of 1N hydrochloric acid, extracted with chloroform and dried over anhydrous sodium sulfate. Distilling the solvent off under reduced pressure, 52.5 mg of the title compound was obtained.

後処理

  1. temperatureunder heating
  2. customThe reaction liquid
  3. extractionextracted with chloroform
  4. dry with materialdried over anhydrous sodium sulfate
  5. distillationDistilling the solvent off under reduced pressure

出典と根拠

ORDレコード
ord-535d0ea3672041d9a8a7efe14f219fa0
出典データセット
uspto-grants-2008_11
特許番号
US07452908B2

反応ノート

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