Thionyl Chloride → 3-Ethylcyclobutanecarboxylic acid chloride

HRID 27294

反応式

HRID 27294 の反応式
[CH2:1]([CH:3]1[CH2:6][CH:5]([C:7]([OH:9])=O)[CH2:4]1)[CH3:2].S(Cl)([Cl:12])=O>>[CH2:1]([CH:3]1[CH2:6][CH:5]([C:7]([Cl:12])=[O:9])[CH2:4]1)[CH3:2]

参加物

3

反応物 2

HCID 24386Thionyl ChlorideHCID 47796Cyclobutanecarboxylic acid, 3-ethyl-

生成物 1

HCID 450812713-Ethylcyclobutanecarboxylic acid chloride収率 60.6%

実験手順

A mixture of 3.3 g (0.027 mole) of 3-ethylcyclobutanecarboxylic acid (prepared in 1E) and 9.4 g (5.7 ml, 0.080 mole) of thionyl chloride was prepared and allowed to stir at room temperature for about 15 hr. Excess thionyl chloride was removed by distillation at atmospheric pressure. The residue was distilled at reduced pressure to yield 2.4 g of the title compound having the following physical characteristics:

後処理

  1. customwas prepared
  2. customExcess thionyl chloride was removed by distillation at atmospheric pressure
  3. distillationThe residue was distilled at reduced pressure

出典と根拠

ORDレコード
ord-bd5aa059603b4de884c3fae56ebe28c3
出典データセット
uspto-grants-1980_09
特許番号
US04220795

関連ノート

読み込み中…