Sodium Hydroxide → 1-Aminoanthraquinone

HRID 273912ノート

反応式

HRID 273912 の反応式
C(OC([NH:11][C:12]1[C:25]2[C:24](=[O:26])[C:23]3[C:18](=[CH:19][CH:20]=[CH:21][CH:22]=3)[C:17](=[O:27])[C:16]=2[CH:15]=[CH:14][CH:13]=1)=O)C1C=CC=CC=1.[OH-].[Na+]>C(O)C>[NH2:11][C:12]1[C:25]2[C:24](=[O:26])[C:23]3[C:18](=[CH:19][CH:20]=[CH:21][CH:22]=3)[C:17](=[O:27])[C:16]=2[CH:15]=[CH:14][CH:13]=1

参加物

4

反応物 2

HCID 14798Sodium HydroxideHCID 11024734HCID 11024734、化合物

生成物 1

HCID 67101-Aminoanthraquinone収率 96.1%

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒

実験手順

0.50 g of 1-benzyloxycarbonylaminoanthraquinone, 25 ml of ethanol and 25 ml of 50% strength aqueous sodium hydroxide solution were heated under reflux for 6 hours and the solution was then concentrated in vacuo. The residue was taken up in chloroform/water, the phases were separated and the organic phase was washed twice with water. The organic phase was concentrated in vacuo and 0.30 g of 1-aminoanthraquinone (99% pure; 95% of theory) was obtained.

後処理

  1. temperatureunder reflux for 6 hours
  2. concentrationthe solution was then concentrated in vacuo
  3. customthe phases were separated
  4. washthe organic phase was washed twice with water
  5. concentrationThe organic phase was concentrated in vacuo

出典と根拠

ORDレコード
ord-49308a0a18cb40239263b61309c0a178
出典データセット
uspto-grants-1995_02
特許番号
US05387704

反応ノート

読み込み中…