1,4-Naphthoquinone → HCID 11024734、化合物

HRID 273913ノート

反応式

HRID 273913 の反応式
[C:1]1(=[O:12])[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[C:4](=[O:11])[CH:3]=[CH:2]1.[CH:13]([NH:17][C:18](=[O:27])[O:19][CH2:20][C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1)=[CH:14][CH:15]=[CH2:16]>[Cu]Cl.N1C=CC=CC=1>[CH2:20]([O:19][C:18]([NH:17][C:13]1[C:2]2[C:1](=[O:12])[C:10]3[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=3)[C:4](=[O:11])[C:3]=2[CH:16]=[CH:15][CH:14]=1)=[O:27])[C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1

参加物

5

反応物 2

HCID 85301,4-NaphthoquinoneHCID 329894HCID 329894、化合物

生成物 1

HCID 11024734HCID 11024734、化合物収率 89.6%

試薬・触媒・溶媒 2

HCID 62652Cuprous chloride触媒HCID 1049Pyridine溶媒

実験手順

0.79 g of 1,4-naphthoquinone, 1.07 g of benzyl N-butadienylcarbamate, 25 mg of copper(I) chloride and 25 ml of pyridine were stirred at 25° C. for 30 hours under a gentle stream of air and the solution was then concentrated in vacuo. The residue was taken up in chloroform, the solution was extracted with 2N hydrochloric acid and the organic phase was concentrated in vacuo. 1.60 g of 1-benzyloxycarbonylaminoanthraquinone (83% pure; 75% of theory) were obtained.

後処理

  1. concentrationthe solution was then concentrated in vacuo
  2. extractionthe solution was extracted with 2N hydrochloric acid
  3. concentrationthe organic phase was concentrated in vacuo

出典と根拠

ORDレコード
ord-619a42ef13084a79878c82376376f7d1
出典データセット
uspto-grants-1995_02
特許番号
US05387704

反応ノート

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