Phenylacetonitrile → 2-(alpha-Cyanobenzylidene)perhydroazepine
反応式
CO[C:3]1[CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][N:9]=1.[CH2:10]([C:17]#[N:18])[C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1.N12CCCCC1C=NCCC2>>[C:17]([C:10](=[C:3]1[CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][NH:9]1)[C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1)#[N:18]参加物
4
実験手順
Stir 8.1 g of caprolactim methyl ether and 5.0 g of benzyl cyanide with 0.6 g of 1,5-diazabicyclo [5.4.0]undec-5-ene under nitrogen for 48 hours at 130°; distil off any excess benzyl cyanide under a high vacuum, and rub down the thus-produced residue with a little methyl alcohol before filtering to obtain 3.78 g of the title compound. Recrystallize from methyl alcohol to obtain a purer product, MP 108° to 113°.
後処理
- customdistil off any excess benzyl cyanide under a high vacuum, and rub down the thus-produced residue with a little methyl alcohol
- filtrationbefore filtering
出典と根拠
- ORDレコード
- ord-c9465b3257644a528074cceea561fa4e
- 出典データセット
- uspto-grants-1980_09
- 特許番号
- US04221788
反応ノート
読み込み中…