3,4-Diaminopyridine → HCID 178441556、化合物

HRID 274333

反応式

HRID 274333 の反応式
[NH2:1][C:2]1[CH:3]=[N:4][CH:5]=[CH:6][C:7]=1[NH2:8].[C:9](O)(=O)[CH2:10][CH2:11][CH2:12][CH3:13]>>[CH2:10]([C:9]1[NH:8][C:7]2[CH:6]=[CH:5][N:4]=[CH:3][C:2]=2[N:1]=1)[CH2:11][CH2:12][CH3:13]

参加物

3

反応物 2

HCID 59183,4-DiaminopyridineHCID 7991Pentanoic Acid

生成物 1

HCID 178441556HCID 178441556、化合物収率 99.6%

反応条件

温度
70 °C

実験手順

A mixture of 3 g of 3,4-diamino-pyridine and 8.28 g of valeric acid was heated to 70° C. for 18 hours and the reaction medium was chromatographed on silica (eluant: ethyl acetatemethanol (8-2)) to obtain 4.8 g of the expected product which was used as is for the following step.

後処理

  1. customthe reaction medium was chromatographed on silica (eluant: ethyl acetatemethanol (8-2))

出典と根拠

ORDレコード
ord-ad0e57e92b4348ebbe384289d16ea0c2
出典データセット
uspto-grants-1995_02
特許番号
US05389634

関連ノート

読み込み中…