Diaminomaleonitrile → HCID 178510651、化合物

HRID 274555

反応式

HRID 274555 の反応式
[OH:1][C:2]1[CH:3]=[C:4]([C:12](=O)[C:13]([O:15]CCCCCC)=O)[CH:5]=[C:6]([N+:9]([O-:11])=[O:10])[C:7]=1[OH:8].[NH2:23]/[C:24](/[C:29]#[N:30])=[C:25](\[NH2:28])/[C:26]#[N:27]>C(O)C>[OH:15][C:13]1[N:28]=[C:25]([C:26]#[N:27])[C:24]([C:29]#[N:30])=[N:23][C:12]=1[C:4]1[CH:5]=[C:6]([N+:9]([O-:11])=[O:10])[C:7]([OH:8])=[C:2]([OH:1])[CH:3]=1

参加物

4

反応物 2

HCID 2723951DiaminomaleonitrileHCID 5747978Benzeneacetic acid, 3,4-dihydroxy-5-nitro-alpha-oxo-, hexyl ester

生成物 1

HCID 178510651HCID 178510651、化合物

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒

実験手順

A solution of 4.0 g of n-hexyl 3,4-dihydroxy-5-nitrophenylglyoxylate and 1.5 g of diaminomaleonitrile in 35 ml of ethanol is heated to boiling under reflux for 24 hours. The alcohol is then distilled , the residue is dissolved in ether, washed with water, dried over sodium sulfate, filtered and evaporated. There is obtained 6-hydroxy-5-(3,4-dihydroxy-5-nitrophenyl)-2,3-pyrazinedicarbonitrile of m.p. >300° (from ether/methylene chloride).

後処理

  1. temperatureunder reflux for 24 hours
  2. distillationThe alcohol is then distilled
  3. dissolutionthe residue is dissolved in ether
  4. washwashed with water
  5. dry with materialdried over sodium sulfate
  6. filtrationfiltered
  7. customevaporated

出典と根拠

ORDレコード
ord-ed91491a11fc41c0a0bcbbb9b007c5b5
出典データセット
uspto-grants-1995_02
特許番号
US05389653

関連ノート

読み込み中…