Benzoyl Peroxide → HCID 20092923、化合物

HRID 274585ノート

反応式

HRID 274585 の反応式
[C:1]([C:3]1[C:4]([C:9]2[CH:14]=[CH:13][C:12]([CH3:15])=[CH:11][CH:10]=2)=[N:5][CH:6]=[N:7][CH:8]=1)#[N:2].[Br:16]N1C(=O)CCC1=O.C(OOC(=O)C1C=CC=CC=1)(=O)C1C=CC=CC=1>C(Cl)(Cl)(Cl)Cl>[Br:16][CH2:15][C:12]1[CH:13]=[CH:14][C:9]([C:4]2[C:3]([C:1]#[N:2])=[CH:8][N:7]=[CH:6][N:5]=2)=[CH:10][CH:11]=1

参加物

5

反応物 3

HCID 7187Benzoyl PeroxideHCID 67184N-bromobutanimideHCID 200929434-(4-Methylphenyl)-5-pyrimidinecarbonitrile

生成物 1

HCID 20092923HCID 20092923、化合物収率 105.5%

試薬・触媒・溶媒 1

HCID 5943Carbon Tetrachloride溶媒

実験手順

A mixture of 5-cyano-4-(p-tolyl)pyrimidine (2.5 g, 12.8 mmol), N-bromosuccinimide (2.4 g, 13.5 mmol) and benzoyl peroxide (catalytic amount) in carbon tetrachloride (100 ml) was refluxed under light radiation for 1 hour. After cooling, insoluble materials were removed and the filtrate was concentrated to dryness to afford a yellow syrup (3.7 g, 100%).

後処理

  1. temperaturewas refluxed under light radiation for 1 hour
  2. temperatureAfter cooling
  3. custominsoluble materials were removed
  4. concentrationthe filtrate was concentrated to dryness

出典と根拠

ORDレコード
ord-8a0010ea70a54f8cb71f7da42286d8b5
出典データセット
uspto-grants-1995_02
特許番号
US05389641

反応ノート

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