Thionyl Chloride → 2,3,5-Trichlorophenylacetyl chloride

HRID 274834ノート

反応式

HRID 274834 の反応式
[Cl:1][C:2]1[C:7]([Cl:8])=[CH:6][C:5]([Cl:9])=[CH:4][C:3]=1[CH2:10][C:11]([OH:13])=O.S(Cl)([Cl:16])=O>C(Cl)(Cl)(Cl)Cl>[Cl:1][C:2]1[C:7]([Cl:8])=[CH:6][C:5]([Cl:9])=[CH:4][C:3]=1[CH2:10][C:11]([Cl:16])=[O:13]

参加物

4

反応物 2

HCID 24386Thionyl ChlorideHCID 186876252,3,5-Trichlorophenylacetic acid

生成物 1

HCID 214781102,3,5-Trichlorophenylacetyl chloride

試薬・触媒・溶媒 1

HCID 5943Carbon Tetrachloride溶媒

実験手順

A suspension of 6.0 grams (0.023 mole) of 2,3,5-trichlorophenylacetic acid in about 125 mL of carbon tetrachloride was stirred, and 5 mL of thionyl chloride was added. The reaction mixture was then warmed to reflux, where it was stirred for about 30 minutes. After this time the reaction mixture was concentrated under reduced pressure, yielding 6.4 grams of 2,3,5-trichlorophenylacetyl chloride.

後処理

  1. temperatureThe reaction mixture was then warmed
  2. temperatureto reflux
  3. stirringwhere it was stirred for about 30 minutes
  4. concentrationAfter this time the reaction mixture was concentrated under reduced pressure

出典と根拠

ORDレコード
ord-48b2e19bc4d145b29dcd0b1020a8fc77
出典データセット
uspto-grants-1995_02
特許番号
US05391541

反応ノート

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