N-ethyl-N'-[2-(2-pyrazinylmethylamino)ethyl]thiourea → N-cyano-N'-ethyl-N"-[2-(2-pyrazinylmethylamino)ethyl]-guanidine

HRID 27527

反応式

HRID 27527 の反応式
[CH2:1]([NH:3][C:4]([NH:6][CH2:7][CH2:8][NH:9][CH2:10][C:11]1[CH:16]=[N:15][CH:14]=[CH:13][N:12]=1)=S)[CH3:2].[N:17]#[C:18][NH2:19].[Pb]>>[C:18]([NH:19][C:4]([NH:3][CH2:1][CH3:2])=[N:6][CH2:7][CH2:8][NH:9][CH2:10][C:11]1[CH:16]=[N:15][CH:14]=[CH:13][N:12]=1)#[N:17]

参加物

3

実験手順

Reacting N-(2-pyrazinylmethyl)ethylenediamine with ethyl isothiocyanate by the procedure of Example 3 and chromatographing gives N-ethyl-N'-[2-(2-pyrazinylmethylamino)ethyl]thiourea. Reacting this thiourea with lead cyanamide by the procedure of Example 3 gives N-cyano-N'-ethyl-N"-[2-(2-pyrazinylmethylamino)ethyl]-guanidine.

出典と根拠

ORDレコード
ord-7d07c31946774c9a937670d1f0fe2b07
出典データセット
uspto-grants-1980_09
特許番号
US04221802

関連ノート

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