6-Nitro-o-anisidine → 3-Methoxybenzene-1,2-diamine

HRID 275787

反応式

HRID 275787 の反応式
[NH2:1][C:2]1[C:7]([N+:8]([O-])=O)=[CH:6][CH:5]=[CH:4][C:3]=1[O:11][CH3:12]>C(OCC)(=O)C.[Pd]>[NH2:1][C:2]1[C:7]([NH2:8])=[CH:6][CH:5]=[CH:4][C:3]=1[O:11][CH3:12]

参加物

4

反応物 1

HCID 854916-Nitro-o-anisidine

生成物 1

HCID 1842683-Methoxybenzene-1,2-diamine収率 101.9%

試薬・触媒・溶媒 2

HCID 23938Palladium触媒HCID 8857Ethyl Acetate溶媒

実験手順

2-Amino-3-nitroanisole (4.3 g) was hydrogenated in ethyl acetate (200 ml) using catalytic 10% palladium on charcoal under an atmosphere of hydrogen at ambient temperature. Once complete the reaction mixture was filtered through Celite and the filtrate evaporated in vacuo to afford the title compound as a brown liquid (3.60 g).

後処理

  1. customat ambient temperature
  2. filtrationwas filtered through Celite
  3. customthe filtrate evaporated in vacuo

出典と根拠

ORDレコード
ord-1931361c855c4e49b5bf142cad92b2bd
出典データセット
uspto-grants-2002_03
特許番号
US06353010B1

関連ノート

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