4-Isopropylbenzyl chloride → 3-Chloro-4-(4'-isopropylbenzyloxy) phenylacetic acid

HRID 27603

反応式

HRID 27603 の反応式
[CH:1]([C:4]1[CH:11]=[CH:10][C:7]([CH2:8]Cl)=[CH:6][CH:5]=1)([CH3:3])[CH3:2].[Cl:12][C:13]1[CH:14]=[C:15]([CH2:20][C:21]([O:23]C)=[O:22])[CH:16]=[CH:17][C:18]=1[OH:19]>CO.O>[Cl:12][C:13]1[CH:14]=[C:15]([CH2:20][C:21]([OH:23])=[O:22])[CH:16]=[CH:17][C:18]=1[O:19][CH2:8][C:7]1[CH:10]=[CH:11][C:4]([CH:1]([CH3:3])[CH3:2])=[CH:5][CH:6]=1

参加物

4

反応物 2

HCID 749164-Isopropylbenzyl chlorideHCID 92625Methyl 3-chloro-4-hydroxyphenylacetate

生成物 1

HCID 510572333-Chloro-4-(4'-isopropylbenzyloxy) phenylacetic acid

試薬・触媒・溶媒 1

HCID 22242641Methanol--water (1/1)溶媒

実験手順

3-chloro-4-(4'-isopropylbenzyloxy) phenylacetic acid was prepared in accordance with the procedure designated (f) above by reacting 4-isopropylbenzyl chloride with methyl 3-chloro-4-hydroxyphenylacetate. The resultant product evidenced a melting point of 146.5°-148° C. in a methanol-water 2:1 mixture.

出典と根拠

ORDレコード
ord-2f92acfef37b4fc4a8710866b2b3d64a
出典データセット
uspto-grants-1980_09
特許番号
US04221919

関連ノート

読み込み中…