Thionyl Chloride → HCID 18316160、化合物
反応式
[CH:1]1([NH:6][CH2:7][CH2:8]O)[CH2:5][CH2:4][CH2:3][CH2:2]1.O=S(Cl)[Cl:12]>>[CH:1]1([NH:6][CH2:7][CH2:8][Cl:12])[CH2:5][CH2:4][CH2:3][CH2:2]1参加物
3
実験手順
2-Hydroxyethylamine and cyclopentanone were reacted according to Method B4b, Step 1 to afford 4-aza-1-oxaspiro[4.4]nonane. The oxazolidine was reduced according to method B4b, Step 2 to afford N-cyclopentyl-N-(2-hydroxyethyl)amine. The alcohol was reacted with SOCl2 according to Method B7c to afford N-cyclopentyl-N-(2-chloroethyl)amine. The amine was reacted with 2,3-dichlorophenyl isothiocyanate according to Method C1d to afford 2-(2,3-dichlorophenylimino)-3-cyclopentyl-1,3-thiazolidine.
出典と根拠
- ORDレコード
- ord-a43bd6f7f8eb400792432c53017a843f
- 出典データセット
- uspto-grants-2002_03
- 特許番号
- US06353006B1
反応ノート
読み込み中…