Thionyl Chloride → N-cyclopentylmethyl-N-(2-chloroethyl)ammonium chloride

HRID 276374

反応式

HRID 276374 の反応式
[CH:1]1([CH2:6][NH:7][CH2:8][CH2:9]O)[CH2:5][CH2:4][CH2:3][CH2:2]1.O=S(Cl)[Cl:13]>>[Cl-:13].[CH:1]1([CH2:6][NH2+:7][CH2:8][CH2:9][Cl:13])[CH2:5][CH2:4][CH2:3][CH2:2]1

参加物

3

反応物 2

HCID 24386Thionyl ChlorideHCID 18316431N-cyclopentylmethyl-N-(2-hydroxyethyl)amine

生成物 1

HCID 18316280N-cyclopentylmethyl-N-(2-chloroethyl)ammonium chloride

実験手順

2-Hydroxyethylamine was reacted with cyclopentylmethyl bromide according to Method B2a to give N-cyclopentylmethyl-N-(2-hydroxyethyl)amine. The alcohol was reacted with SOCl2 according to Method B7c to give N-cyclopentylmethyl-N-(2-chloroethyl)ammonium chloride. The chloroethylamine was reacted with 2-methyl-4-nitrophenyl isothiocyanate to give 2-(2-methyl-4-nitrophenylimino)-3-(cyclopentylmethyl)-1,3-thiazolidine.

出典と根拠

ORDレコード
ord-25ea4c21ce9c4af1abc78cd526a1491a
出典データセット
uspto-grants-2002_03
特許番号
US06353006B1

関連ノート

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