Thionyl Chloride → N-cyclohexylmethyl-N-(2-chloroethyl)ammonium chloride
反応式
[CH:1]1([CH2:7][NH:8][CH2:9][CH2:10]O)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.O=S(Cl)[Cl:14]>>[Cl-:14].[CH:1]1([CH2:7][NH2+:8][CH2:9][CH2:10][Cl:14])[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1参加物
3
実験手順
2-Hydroxyethylamine was reacted with cyclohexylmethyl bromide according to Method B2a to give N-cyclohexylmethyl-N-(2-hydroxyethyl)amine. The alcohol was reacted with SOCl2 according to Method B7c to give N-cyclohexylmethyl-N-(2-chloroethyl)ammonium chloride. The chloroethylamine was reacted with 2-methoxy4-nitrophenyl isothiocyanate to give 2-(2-methoxy-4-nitrophenylimino)-3-(cyclohexylmethyl)-1,3-thiazolidine.
出典と根拠
- ORDレコード
- ord-22f796017255461d9562aa39e8069e5b
- 出典データセット
- uspto-grants-2002_03
- 特許番号
- US06353006B1
反応ノート
読み込み中…