Benzylethanolamine → N-(2-Chloroethyl)benzylamine hydrochloride
反応式
[CH2:1]([NH:8][CH2:9][CH2:10]O)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.O=S(Cl)[Cl:14]>>[Cl-:14].[CH2:1]([NH2+:8][CH2:9][CH2:10][Cl:14])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1参加物
3
実験手順
2-Hydroxyethylamine was reacted with benzyl bromide according to Method B2a to give N-benzyl-N-(2-hydroxyethyl)amine. The alcohol was reacted with SOCl2 according to Method B7c to give N-benzyl-N-(2-chloroethyl)ammonium chloride. The chloroethylamine was reacted with 2-methyl-4-nitrophenyl isothiocyanate to give 2-(2-methyl-4-nitrophenylimino)-3-benzyl-1,3-thiazolidine.
出典と根拠
- ORDレコード
- ord-15512d3eda824bbe9f9ce97a33317ae9
- 出典データセット
- uspto-grants-2002_03
- 特許番号
- US06353006B1
反応ノート
読み込み中…