4-ethoxymethylene-2-(1)-naphthyl-5(4H)-oxazolone → 4-{4-[(benzylidene-amino)-methyl]-piperidin-1-ylmethylene}-2-naphthalen-1-yl-4H-oxazol-5-one

HRID 276787

反応式

C(O[CH:4]=[C:5]1[C:9](=[O:10])[O:8][C:7]([C:11]2[C:20]3[C:15](=[CH:16][CH:17]=[CH:18][CH:19]=3)[CH:14]=[CH:13][CH:12]=2)=[N:6]1)C.[CH:21](=[N:28][CH2:29][CH:30]1[CH2:35][CH2:34][NH:33][CH2:32][CH2:31]1)[C:22]1[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=1>O1CCCC1>[CH:21](=[N:28][CH2:29][CH:30]1[CH2:31][CH2:32][N:33]([CH:4]=[C:5]2[C:9](=[O:10])[O:8][C:7]([C:11]3[C:20]4[C:15](=[CH:16][CH:17]=[CH:18][CH:19]=4)[CH:14]=[CH:13][CH:12]=3)=[N:6]2)[CH2:34][CH2:35]1)[C:22]1[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=1

参加物

実験手順

To a solution of 4-ethoxymethylene-2-naphthalen-1-yl-4H-oxazol-5-one (11.40 g, 43 mmol) in tetrahydrofuran, benzylidene-piperidin-4-ylmethyl-amine (8.60 g, 43 mmol) was added, and the mixture was stirred at room temperature for 24 h. The reaction mixture was concentrated under reduced pressure to yield 4-{4-[(benzylidene-amino)-methyl]-piperidin-1-ylmethylene}-2-naphthalen-1-yl-4H-oxazol-5-one.

後処理

concentrationThe reaction mixture was concentrated under reduced pressure

出典と根拠

ORDレコード: ord-0ea03cc5fb7f4f1cb7f181c2ebd1448a
出典データセット: uspto-grants-2002_03
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US06355641B1

反応式

参加物

反応物 2

生成物 1

試薬・触媒・溶媒 1

実験手順

後処理

出典と根拠

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