1-Azido-3-(3-methoxyphenyl)-1-phenylpropane → 3-(3-Methoxyphenyl)-1-phenylpropylamine
反応式
[N:1]([CH:4]([C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1)[CH2:5][CH2:6][C:7]1[CH:12]=[CH:11][CH:10]=[C:9]([O:13][CH3:14])[CH:8]=1)=[N+]=[N-]>CCO.[Pd]>[CH3:14][O:13][C:9]1[CH:8]=[C:7]([CH2:6][CH2:5][CH:4]([NH2:1])[C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=2)[CH:12]=[CH:11][CH:10]=1参加物
4
実験手順
A solution of the product from Step B (1.08 g, 3.7 mmol) in 30 mL of EtOH containing Pd/C (10%, 100 mg) was stirred at ambient temperature under 1 Atm. of H2 for 20 hours. The reaction mixture was filtered to provide the title product as a clear colorless oil which was sufficiently pure for use in the next step.
後処理
- filtrationThe reaction mixture was filtered
出典と根拠
- ORDレコード
- ord-9d0a4ee5be92430b8bf18e32271c5dab
- 出典データセット
- uspto-grants-2002_03
- 特許番号
- US06358985B1
反応ノート
読み込み中…