Ethyl Bromide → 2-Propoxybenzonitrile
反応式
[OH:1][C:2]1[CH:9]=[CH:8][CH:7]=[CH:6][C:3]=1[C:4]#[N:5].[C:10](=O)([O-])[O-].[K+].[K+].[CH2:16](Br)[CH3:17]>CC(C)=O>[CH2:10]([O:1][C:2]1[CH:9]=[CH:8][CH:7]=[CH:6][C:3]=1[C:4]#[N:5])[CH2:16][CH3:17]参加物
5
実験手順
75 g (630 ml) of 2-hydroxybenzonitrile are refluxed with 174 g (1.26 mol) of potassium carbonate and 232.2 g (1.89 mol) of ethyl bromide in 11 of acetone overnight. The solid is filtered off, the solvent is removed under reduced pressure and the residue is distilled under reduced pressure.
後処理
- filtrationThe solid is filtered off
- customthe solvent is removed under reduced pressure
- distillationthe residue is distilled under reduced pressure
出典と根拠
- ORDレコード
- ord-549ac89516b841d492e7cd44244c1bd6
- 出典データセット
- uspto-grants-2002_03
- 特許番号
- US06362178B1
反応ノート
読み込み中…