Naphthalic anhydride → 5-Bromobenzo[de]isochromene-1,3-dione
反応式
[Br:1]Br.[CH:3]1[CH:4]=[C:5]2[C:10]3=[C:11]([C:13]([O:15][C:16](=[O:17])[C:9]3=[CH:8][CH:7]=[CH:6]2)=[O:14])[CH:12]=1>[N+]([O-])(O)=O>[CH:3]1[CH:12]=[C:11]2[C:13]([O:15][C:16](=[O:17])[C:9]3=[C:10]2[C:5](=[CH:6][C:7]([Br:1])=[CH:8]3)[CH:4]=1)=[O:14]参加物
4
反応条件
- 温度
- 70 °C
実験手順
Bromine (8.2 g, 51.3 mmol) was added to a solution of 1,8-naphthalic anhydride (10.0 g, 50.5 mmol) in 70% nitric acid (200 mL) at 25° C. The mixture was stirred at 70° C. for 2 hours and cooled overnight. The solids that separated were filtered, washed with water, and dried to give 2.0 g of the title compound (Reference: J. C. S., 1938:1764-1767).
後処理
- temperaturecooled overnight
- customThe solids that separated
- filtrationwere filtered
- washwashed with water
- customdried
出典と根拠
- ORDレコード
- ord-93e4ff68a87b49ae878c5747590257c7
- 出典データセット
- uspto-grants-2002_03
- 特許番号
- US06362181B1
反応ノート
読み込み中…