3-(Trifluoromethyl)aniline → 3-oxo-N-[3-(trifluoromethyl)phenyl]butanamide
反応式
[F:1][C:2]([F:11])([F:10])[C:3]1[CH:4]=[C:5]([CH:7]=[CH:8][CH:9]=1)[NH2:6].[CH2:12]=[C:13]1[O:17][C:15](=[O:16])[CH2:14]1>C1C=CC=CC=1>[F:1][C:2]([F:10])([F:11])[C:3]1[CH:4]=[C:5]([CH:7]=[CH:8][CH:9]=1)[NH:6][C:15](=[O:16])[CH2:14][C:13]([CH3:12])=[O:17]参加物
4
実験手順
m-Trifluoromethyl aniline (32.22 g) in benzene was dissolved in benzene and diketene added slowly with mixing. The reaction mixture was allowed to stand at 25° C. The resulting solid product was recrystallized from ethanol to yield 3'-trifluoromethyl acetoacetanilide.
後処理
- additionwith mixing
- customto stand at 25° C
- customThe resulting solid product was recrystallized from ethanol
出典と根拠
- ORDレコード
- ord-e2e79f9094af4c188695b3e1de86223b
- 出典データセット
- uspto-grants-1980_09
- 特許番号
- US04224334
反応ノート
読み込み中…