1-Indanone → 3-Bromo-1-indanone

HRID 279152

反応式

HRID 279152 の反応式
[C:1]1(=[O:10])[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[CH2:3][CH2:2]1.C1C(=O)N([Br:18])C(=O)C1>C(Cl)(Cl)(Cl)Cl>[Br:18][CH:3]1[C:4]2[C:9](=[CH:8][CH:7]=[CH:6][CH:5]=2)[C:1](=[O:10])[CH2:2]1

参加物

4

反応物 2

HCID 67351-IndanoneHCID 67184N-bromobutanimide

生成物 1

HCID 117459123-Bromo-1-indanone

試薬・触媒・溶媒 1

HCID 5943Carbon Tetrachloride溶媒

実験手順

1-Indanone (1 g) and NBS (1.4 g) was mixed with dry CCl4 (20 ml). A catalytic amount of AlBN was added and the mixture was refluxed for 30 minutes and excited with light using 250 W lamp. The mixture was cooled in an ice bath and filtered. The filtrate was concentrated in an evaporator and used without further purification for the next step. Yield was 1.5 g.

後処理

  1. temperaturethe mixture was refluxed for 30 minutes
  2. temperatureThe mixture was cooled in an ice bath
  3. filtrationfiltered
  4. concentrationThe filtrate was concentrated in an evaporator
  5. customused without further purification for the next step

出典と根拠

ORDレコード
ord-c54a0fd89f4a4e89ae60c4b36eb93b67
出典データセット
uspto-grants-2002_03
特許番号
US06362211B1

関連ノート

読み込み中…