Tetrafluoroisophthalic Acid → HCID 10130865、化合物
反応式
F[C:2]1[C:7]([C:8]([OH:10])=[O:9])=[C:6]([F:11])[C:5]([C:12]([OH:14])=[O:13])=[C:4]([F:15])[C:3]=1[F:16].[CH3:17][Mg]Cl>C1COCC1>[F:11][C:6]1[C:5]([C:12]([OH:14])=[O:13])=[C:4]([F:15])[C:3]([F:16])=[C:2]([CH3:17])[C:7]=1[C:8]([OH:10])=[O:9]参加物
4
実験手順
20 g of tetrafluoroisophthalic acid are initially charged in 250 ml of THF and, at from 20 to 40° C., admixed with 88 ml of a 3 molar methylmagnesium chloride solution. Customary aqueous work-up (see Example 3) gives 20.1 g of 2,4,5-trifluoro-6-methylisophthalic acid. The purity of the product is 85% by HPLC.
出典と根拠
- ORDレコード
- ord-77d6ae5fa95046f9b9314c9da16b70f2
- 出典データセット
- uspto-grants-2002_03
- 特許番号
- US06362365B1
反応ノート
読み込み中…