2-Chloro-4-nitropyridine 1-oxide → Pyridine, 2-chloro-4-methoxy-, 1-oxide

HRID 279834

反応式

HRID 279834 の反応式
[Na].[CH3:2][O-:3].[Na+].[Cl:5][C:6]1[CH:11]=[C:10]([N+]([O-])=O)[CH:9]=[CH:8][N+:7]=1[O-:15]>CO>[Cl:5][C:6]1[CH:11]=[C:10]([O:3][CH3:2])[CH:9]=[CH:8][N+:7]=1[O-:15]

参加物

5

反応物 3

HCID 844332-Chloro-4-nitropyridine 1-oxideHCID 5360545SodiumHCID 10942334Sodium Methoxide

生成物 1

HCID 15593755Pyridine, 2-chloro-4-methoxy-, 1-oxide

試薬・触媒・溶媒 1

HCID 887Methanol溶媒2 回

実験手順

Sodium (0.46 g) is dissolved in absolute methanol (50 ml) and the resultant solution of sodium methoxide is added to a solution of 2-chloro-4-nitropyridine-1-oxide (3.5 g, prepared as described in Example 1) in methanol (10 ml). The reaction mixture is allowed to stand at room temperature for 50 hours and is then subjected to rotary evaporation to give 2-chloro-4-methoxypyridine-1-oxide.

後処理

  1. customis then subjected to rotary evaporation

出典と根拠

ORDレコード
ord-20c5b2c1ecd64b7c88f1f08ccc54e6e7
出典データセット
uspto-grants-1986_05
特許番号
US04587240

関連ノート

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