Hydrochloric Acid → HCID 14631382、化合物
反応式
[CH3:1][O:2][CH2:3][CH2:4][O:5][CH:6](O)[CH3:7].[CH2:9]=[O:10].[Cl-:11].[Ca+2].[Cl-].Cl>C(Cl)Cl>[CH3:1][O:2][CH2:3][CH2:4][O:5][CH2:6][CH2:7][O:10][CH2:9][Cl:11]参加物
6
反応条件
- 温度
- -5 °C
実験手順
Hydrogen chloride gas was bubbled into a mixture containing 24 g (200 mmol) of (2-methoxyethoxy)ethanol, 6.0 g (200 mmol) of paraformaldehyde and 22 g (200 mmol) of powdered calcium chloride with stirring and cooling to -5° C. The HCl was continued for 4 hours as the temperature was allowed to rise gradually to 8° C. Celite was added and the reaction filtered. The filtrate was evaporated leaving 29.8 g of a cloudy oil. The oil was dissolved in methylene chloride and dried over molecular sieves. Evaporation furnished 19.3 g of [2-(2-methoxyethoxy)ethoxy]methyl chloride as an oil which was characterized by nuclear magnetic resonance.
後処理
- customHydrogen chloride gas was bubbled into a mixture
- customto rise gradually to 8° C
- additionCelite was added
- filtrationthe reaction filtered
- customThe filtrate was evaporated
- customleaving 29.8 g of a cloudy oil
- customdried over molecular sieves
- customEvaporation
出典と根拠
- ORDレコード
- ord-f6bf9af3c37e4176ac961fcb590948dc
- 出典データセット
- uspto-grants-1986_05
- 特許番号
- US04587247
反応ノート
読み込み中…