HCID 14203475、化合物 → 2-(4-aminophenyl)-5,6-dihydro-4H-1,3,4-oxadiazin-5-one

HRID 279861ノート

反応式

HRID 279861 の反応式
[N+:1]([C:4]1[CH:9]=[CH:8][C:7]([C:10]2[O:11][CH2:12][C:13](=[O:16])[NH:14][N:15]=2)=[CH:6][CH:5]=1)([O-])=O>C(OCC)(=O)C.[Pd]>[NH2:1][C:4]1[CH:5]=[CH:6][C:7]([C:10]2[O:11][CH2:12][C:13](=[O:16])[NH:14][N:15]=2)=[CH:8][CH:9]=1

参加物

4

反応物 1

HCID 14203475HCID 14203475、化合物

生成物 1

HCID 147428442-(4-aminophenyl)-5,6-dihydro-4H-1,3,4-oxadiazin-5-one

試薬・触媒・溶媒 2

HCID 23938Palladium触媒HCID 8857Ethyl Acetate溶媒

実験手順

A solution of 2-p-nitrophenyl-4H,6H-1,3,4-oxadiazin-5-one (Example 17; 2.2 g.) in ethyl acetate (250 ml.) was hydrogenated in the presence of a 5% palladium-on-charcoal catalyst at laboratory temperature and atmospheric pressure until 670 ml. of hydrogen had been absorbed. The mixture was filtered and the filtrate was evaporated to dryness. There was thus obtained as solid residue 2-p-aminophenyl-4H,6H-1,3,4-oxadiazin-5-one, m.p. 253°-255° C. (with decomposition).

後処理

  1. customof hydrogen had been absorbed
  2. filtrationThe mixture was filtered
  3. customthe filtrate was evaporated to dryness

出典と根拠

ORDレコード
ord-25d3b7e5053a495092c033fd514f0c81
出典データセット
uspto-grants-1986_05
特許番号
US04587246

反応ノート

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