2,3-Dihydro-2,4-dimethyl-7-nitrobenzofuran → HCID 13575669、化合物

HRID 279891ノート

反応式

HRID 279891 の反応式
[CH3:1][CH:2]1[CH2:6][C:5]2[C:7]([CH3:14])=[CH:8][CH:9]=[C:10]([N+:11]([O-])=O)[C:4]=2[O:3]1.[H][H]>[Ni].O1CCCC1>[NH2:11][C:10]1[C:4]2[O:3][CH:2]([CH3:1])[CH2:6][C:5]=2[C:7]([CH3:14])=[CH:8][CH:9]=1

参加物

5

反応物 2

HCID 135756682,3-Dihydro-2,4-dimethyl-7-nitrobenzofuranHCID 178418361HCID 178418361、化合物

生成物 1

HCID 13575669HCID 13575669、化合物

試薬・触媒・溶媒 2

HCID 935Nickel触媒HCID 8028Tetrahydrofuran溶媒

実験手順

A mixture of 24.3 g of 1C, 200 ml of tetrahydrofuran (THF) and 2 g of activated Raney nickel catalyst was treated with hydrogen (40 psig) in a Parr shaker three hours, then filtered. The solvent was evaporated from the filtrate to give 7-amino-2,3-dihydro-2,4-dimethylbenzofuran (1D), as an amber syrup.

後処理

  1. filtrationfiltered
  2. customThe solvent was evaporated from the filtrate

出典と根拠

ORDレコード
ord-9af60e78aead4d09ba54008378703f3b
出典データセット
uspto-grants-1986_05
特許番号
US04587259

反応ノート

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