Methyl iodide → 7-Methoxy-4-methyl-4H-benzo[1,4]oxazin-3-one
反応式
[O:1]=[C:2]1[NH:7][C:6]2[CH:8]=[CH:9][C:10]([O:12][CH3:13])=[CH:11][C:5]=2[O:4][CH2:3]1.CI.[C:16](=O)([O-])[O-].[K+].[K+]>CC(C)=O>[O:1]=[C:2]1[N:7]([CH3:16])[C:6]2[CH:8]=[CH:9][C:10]([O:12][CH3:13])=[CH:11][C:5]=2[O:4][CH2:3]1参加物
5
実験手順
Following the procedure of Example 1, 21.7 g of 3-oxo-7-methoxy-3,4-dihydro-2H-[1,4]benzoxazine and 19.88 g of methyl iodide were reacted in 600 ml of acetone in the presence of 19.32 g of solid potassium carbonate. The reaction was carried out, and the product isolated and purified by the procedure of Example 1 to yield 3-oxo-4-methyl-7-methoxy-3,4-dihydro-2H-[1,4]benzoxazine; yield=92%; molecular ion by mass spectrum=193.
後処理
- customthe product isolated
- custompurified by the procedure of Example 1
出典と根拠
- ORDレコード
- ord-ff92bffa867c41b3a5582dbc3d2f30b7
- 出典データセット
- uspto-grants-1986_05
- 特許番号
- US04587336
反応ノート
読み込み中…