Hydrochloric Acid → 4-Nitro-3-phenyl-L-alanine
反応式
[NH2:1][C@H:2]([C:10]([OH:12])=[O:11])[CH2:3][C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1.[N+:13]([O-])([OH:15])=[O:14].Cl>S(=O)(=O)(O)O>[N+:13]([C:7]1[CH:8]=[CH:9][C:4]([CH2:3][C@@H:2]([C:10]([OH:12])=[O:11])[NH2:1])=[CH:5][CH:6]=1)([O-:15])=[O:14]参加物
5
実験手順
Using the procedure of Bergel and Stock as set forth in J. Chem. Soc., 2409-2417 (1954) L-phenylalanine (50 g) was treated with a mixture of concentrated sulfuric acid (150 ml), and fuming nitric acid (28 ml) to produce the nitro compound Yield 26.9 g (43%) mp 232°-234° C., [α]D25 =+9.6° (c=1.77, 1N HCl).
出典と根拠
- ORDレコード
- ord-bcffd1e26f1f46a8acd5510ab76f2131
- 出典データセット
- uspto-grants-1986_05
- 特許番号
- US04587046
反応ノート
読み込み中…