化工社化工社 化学情報印刷レポート · 研究参考用
Ethanol → (R)-2-Acetamido-3-(4-nitrophenyl)propanoic acid
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Ethanol | HCID 702 | — |
| 反応物 | Acetic Anhydride | HCID 7918 | — |
| 反応物 | p-Nitro-D-phenylalanine | HCID 679497 | — |
| 溶媒 | Sodium Hydroxide | HCID 14798 | — |
| 生成物 | (R)-2-Acetamido-3-(4-nitrophenyl)propanoic acid | HCID 7039504 | — |
反応手順
Compound 6 (6.20 g) was acetylated with acetic anhydride (9 ml) in aqueous sodium hydroxide at pH 9 and 4° C. according to the procedure of Yoshida and Ishii [J. Biochem., 71, 185-191 (1972)]. Obtained 5.32 g (71.4%), mp 165°-166° C., [α]D25 =-46.2 °(c =2.8, ethanol)
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04587046 |
| 出典データセット | uspto-grants-1986_05 |
| ORD ID | ord-f4dd3204b88940678314b4ae1017e8ff |
| 出典メモ | uspto-grants-1986_05 |