Hydrochloric Acid → 2,2,3,3-Tetrafluoro-3-methoxypropanoic acid
反応式
[OH-].[Na+].[CH3:3][O:4][C:5]([F:14])([F:13])[C:6]([F:12])([F:11])[C:7]([O:9]C)=[O:8].Cl>O>[CH3:3][O:4][C:5]([F:13])([F:14])[C:6]([F:11])([F:12])[C:7]([OH:9])=[O:8]参加物
5
実験手順
A mixture of 32 g sodium hydroxide, 400 g water and 152 g methyl 3-methoxytetrafluoropropionate was stirred at room temperature until a single liquid layer was obtained. The product was acidified with 37% aqueous HCl and the lower layer separated. The aqueous layer was extracted four times with 50 ml ethyl ether and the combined ether extracts and lower layer distilled to give 103.3 g (73.4%) 3-methoxytetrafluoropropionic acid, b.p. 85°-86° at 20 mm.
後処理
- customwas obtained
- customthe lower layer separated
- extractionThe aqueous layer was extracted four times with 50 ml ethyl ether
- distillationthe combined ether extracts and lower layer distilled
出典と根拠
- ORDレコード
- ord-edf740d373e24212aad77ab5c4df6e06
- 出典データセット
- uspto-grants-1986_05
- 特許番号
- US04590015
反応ノート
読み込み中…