Water → 1-Azido-1-(3-furyl)-1-(4-methyl-5-oxazolyl)ethane

HRID 2835

反応式

HRID 2835 の反応式
[O:1]1[CH:5]=[CH:4][C:3]([C:6]([C:9]2[O:13][CH:12]=[N:11][C:10]=2[CH3:14])(O)[CH3:7])=[CH:2]1.C[Si]([N:19]=[N+:20]=[N-:21])(C)C.B(F)(F)F.O>C1C=CC=CC=1>[N:19]([C:6]([C:3]1[CH:4]=[CH:5][O:1][CH:2]=1)([C:9]1[O:13][CH:12]=[N:11][C:10]=1[CH3:14])[CH3:7])=[N+:20]=[N-:21]

参加物

6

反応物 4

HCID 962WaterHCID 6356Boron trifluorideHCID 78378AzidotrimethylsilaneHCID 97941531-(3-Furyl)-1-(4-methyl-5-oxazolyl)ethanol

生成物 1

HCID 189362941-Azido-1-(3-furyl)-1-(4-methyl-5-oxazolyl)ethane

試薬・触媒・溶媒 1

HCID 241Benzene溶媒

実験手順

1-(3-Furyl)-1-(4-methyl-5-oxazolyl)ethanol (1 g) was suspended in benzene (4 ml). Trimethylsilylazide (822 μl) was added followed by boron trifluoride diethyletherate (770 μl). The mixture was stirred overnight at room temperature, then poured into water and extracted to give the title compound.

後処理

  1. extractionextracted

出典と根拠

ORDレコード
ord-d5df902db51f4973b3595b8e30064e32
出典データセット
uspto-grants-1998_03
特許番号
US05731335

関連ノート

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