Dimethylamine → Dimethylacetoacetamide
反応式
[CH2:1]=[C:2]1[O:6][C:4](=[O:5])[CH2:3]1.CC(C)=O.[CH3:11][NH:12][CH3:13]>C1(C)C=CC=CC=1>[CH3:11][N:12]([CH3:13])[C:4](=[O:5])[CH2:3][C:2](=[O:6])[CH3:1]参加物
4
実験手順
A solution of 9 ml (0.05 mmol) of diketene-acetone adduct in 20 ml of toluene was treated with gaseous dimethylamine at room temperature until the reaction was complete. The solvent was removed in vacuo and the residue was purified by chromatography on silica gel (EtOAc/MeOH 0%→10%) yielding 7.0 g of the title compound.
後処理
- customThe solvent was removed in vacuo
- customthe residue was purified by chromatography on silica gel (EtOAc/MeOH 0%→10%)
出典と根拠
- ORDレコード
- ord-eb592b1203c74e969732293b7513ee02
- 出典データセット
- uspto-grants-1998_03
- 特許番号
- US05731322
反応ノート
読み込み中…