Dimethyl Sulfoxide → 2-(Cyclopropylmethyl-amino)-N-(5-phenoxy-thiophen-2-ylmethyl)-nicotinamide

反応式

[CH3:36][S:37]([CH3:38])=[O:39].[Cl:1][c:2]1[c:3]([C:4](=[O:5])[NH:6][CH2:7][c:8]2[s:9][c:10]([O:13][c:14]3[cH:15][cH:16][cH:17][cH:18][cH:19]3)[cH:11][cH:12]2)[cH:20][cH:21][cH:22][n:23]1.[NH2:24][CH2:25][CH:26]1[CH2:27][CH2:28]1.[OH:29][C:30]([C:31]([F:32])([F:33])[F:34])=[O:35]>>[c:2]1([NH:24][CH2:25][CH:26]2[CH2:27][CH2:28]2)[c:3]([C:4](=[O:5])[NH:6][CH2:7][c:8]2[s:9][c:10]([O:13][c:14]3[cH:15][cH:16][cH:17][cH:18][cH:19]3)[cH:11][cH:12]2)[cH:20][cH:21][cH:22][n:23]1