Tetrahydrofuran → 3-(3-Chloro-thiophene-2-yl)-7-(1-ethyl-propyl)-2,5-dimethyl-pyrazolo[1,5-a]pyrimidine

反応式

[Br:1][c:2]1[s:3][cH:4][cH:5][c:6]1[Cl:7].[CH2:25]1[O:26][CH2:27][CH2:28][CH2:29]1.[CH2:8]([CH3:9])[CH:10]([CH2:11][CH3:12])[c:13]1[cH:14][c:15]([CH3:24])[n:16][c:17]2[n:18]1[n:19][c:20]([CH3:23])[c:21]2[I:22].[Zn:30]>>[c:2]1(-[c:21]2[c:17]3[n:16][c:15]([CH3:24])[cH:14][c:13]([CH:10]([CH2:8][CH3:9])[CH2:11][CH3:12])[n:18]3[n:19][c:20]2[CH3:23])[s:3][cH:4][cH:5][c:6]1[Cl:7]