tert-Butyl isocyanate → 1-[2-Amino-6-(2,6-difluorophenyl)pyrido[2,3-d]pyrimidin-7-yl]-3-tert-butylurea

反応式

[C:21]([CH3:22])([CH3:23])([CH3:24])[N:25]=[C:26]=[O:27].[F:1][c:2]1[c:3](-[c:9]2[cH:10][c:11]3[c:12]([n:13][c:14]([NH2:17])[n:15][cH:16]3)[n:18][c:19]2[NH2:20])[c:4]([F:8])[cH:5][cH:6][cH:7]1>>[F:1][c:2]1[c:3](-[c:9]2[cH:10][c:11]3[c:12]([n:13][c:14]([NH2:17])[n:15][cH:16]3)[n:18][c:19]2[NH:20][C:26]([NH:25][C:21]([CH3:22])([CH3:23])[CH3:24])=[O:27])[c:4]([F:8])[cH:5][cH:6][cH:7]1

参加物

反応物 2

HCID 62412tert-Butyl isocyanate

HCID 218500576-(2,6-Difluoro-phenyl)-pyrido[2,3-d]pyrimidine-2,7-diamine

生成物 1

HCID 53291151-[2-Amino-6-(2,6-difluorophenyl)pyrido[2,3-d]pyrimidin-7-yl]-3-tert-butylurea

出典と根拠

ORDレコード: ord-38347a410bdd45e28dd83fc2ff84b1e9
出典データセット: Training data from https://doi.org/10.1039/C8SC04228D (8/10)
DOI: 10.1039/C8SC04228D

反応ノート

読み込み中…