Tetrahydrofuran → 4-Biphenylsulfonic acid, 4'-amino-

HRID 29494

反応式

HRID 29494 の反応式
[N+:1]([C:4]1[CH:9]=[CH:8][C:7]([C:10]2[CH:15]=[CH:14][C:13]([S:16]([OH:19])(=[O:18])=[O:17])=[CH:12][CH:11]=2)=[CH:6][CH:5]=1)([O-])=O.[Sn](Cl)Cl.C1COCC1>O>[NH2:1][C:4]1[CH:9]=[CH:8][C:7]([C:10]2[CH:15]=[CH:14][C:13]([S:16]([OH:19])(=[O:17])=[O:18])=[CH:12][CH:11]=2)=[CH:6][CH:5]=1

参加物

5

反応物 3

HCID 8028TetrahydrofuranHCID 24479Stannous ChlorideHCID 534258824'-Nitro-4-biphenylsulfonic acid

生成物 1

HCID 957994-Biphenylsulfonic acid, 4'-amino-収率 73.2%

試薬・触媒・溶媒 1

HCID 962Water溶媒

実験手順

4′-Nitro-biphenyl-4-sulfonic acid (1.12 g, 4 mmol) was mixed with tin (II) chloride (5.2 g, 32 mmol) and 40 ml of THF. The mixture was refluxed overnight. The reaction mixture was poured into 80 ml of water and stirred at room temperature for 8 h. The mixture was filtered and the solid was dried under vacuum to provide 0.73 g (73%) of 4′-amino-biphenyl-4-sulfonic acid, obtained as an off-white solid.

後処理

  1. temperatureThe mixture was refluxed overnight
  2. filtrationThe mixture was filtered
  3. customthe solid was dried under vacuum

出典と根拠

ORDレコード
ord-a520dcafb84945c88476d716e5caae5b
出典データセット
uspto-grants-2008_09
特許番号
US07420001B2

関連ノート

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