Carbon Dioxide → 2-Mercapto-3-isopropylbenzoic acid
反応式
[CH:1]([C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=1[SH:10])([CH3:3])[CH3:2].CN(CCN(C)C)C.[Li]CCCC.[C:24](=[O:26])=[O:25]>C1CCCCC1>[SH:10][C:5]1[C:4]([CH:1]([CH3:3])[CH3:2])=[CH:9][CH:8]=[CH:7][C:6]=1[C:24]([OH:26])=[O:25]参加物
6
実験手順
To a solution of 1.0 mmol 2-isopropylthiophenol and 2.2 mmol TMEDA in 2 mL cyclohexane was added 2.2 mmol n-BuLi. Then after stirring 24 h it was added to solid CO2 and stirred for 16 h when extraction and chromatography provided 2-mercapto-3-isopropylbenzoic acid. The methyl ester of this was treated as in example 3 to provide the title compound.
後処理
- stirringstirred for 16 h
- extractionwhen extraction and chromatography
出典と根拠
- ORDレコード
- ord-8bfebd9748154a9780039335f8d6e481
- 出典データセット
- uspto-grants-1998_03
- 特許番号
- US05731432
反応ノート
読み込み中…