Water → 2-chloro-3-(1-cyano-1-methylethyl)-N-[5-({2-[(cyclopropylcarbonyl)amino][1,3]thiazolo[5,4-b]pyridin-5-yl}oxy)-2-fluorophenyl]benzamide

反応式

[CH3:16][N:17]([CH3:18])[CH:19]=[O:20].[CH3:52][N:53]([CH3:54])[C:55](=[O:56])[CH3:57].[Cl:1][c:2]1[c:3]([C:4](=[O:5])[OH:6])[cH:7][cH:8][cH:9][c:10]1[C:11]([CH3:12])([CH3:13])[C:14]#[N:15].[Cl:46][C:47]([C:48]([Cl:49])=[O:50])=[O:51].[NH2:21][c:22]1[cH:23][c:24]([O:25][c:26]2[cH:27][cH:28][c:29]3[c:30]([n:31]2)[s:32][c:33]([NH:35][C:36](=[O:37])[CH:38]2[CH2:39][CH2:40]2)[n:34]3)[cH:41][cH:42][c:43]1[F:44].[OH2:45]>>[Cl:1][c:2]1[c:3]([C:4](=[O:6])[NH:21][c:22]2[cH:23][c:24]([O:25][c:26]3[cH:27][cH:28][c:29]4[c:30]([n:31]3)[s:32][c:33]([NH:35][C:36](=[O:37])[CH:38]3[CH2:39][CH2:40]3)[n:34]4)[cH:41][cH:42][c:43]2[F:44])[cH:7][cH:8][cH:9][c:10]1[C:11]([CH3:12])([CH3:13])[C:14]#[N:15]