O-Xylene → [6-(2,4-Difluoro-phenylamino)-pyridin-3-yl]-(2-methoxy-5-pyridin-2-yl-phenyl)-methanone
反応式
[Br:1][c:2]1[cH:3][cH:4][c:5]([O:25][CH3:26])[c:6]([C:8](=[O:9])[c:10]2[cH:11][n:12][c:13]([NH:16][c:17]3[c:18]([F:24])[cH:19][c:20]([F:23])[cH:21][cH:22]3)[cH:14][cH:15]2)[cH:7]1.[C:54]([O:55][CH3:56])([CH3:57])([CH3:58])[CH3:59].[CH2:27]([Sn:28]([CH2:29][CH2:30][CH2:31][CH3:38])([c:32]1[n:33][cH:34][cH:35][cH:36][cH:37]1)[CH2:39][CH2:40][CH2:41][CH3:42])[CH2:43][CH2:44][CH3:45].[Pd:60]([Cl:61])[Cl:62].[c:46]1([CH3:47])[c:48]([CH3:49])[cH:50][cH:51][cH:52][cH:53]1.[c:63]1([P:64]([c:65]2[cH:66][cH:67][cH:68][cH:69][cH:70]2)[c:71]2[cH:72][cH:73][cH:74][cH:75][cH:76]2)[cH:77][cH:78][cH:79][cH:80][cH:81]1.[c:82]1([P:83]([c:84]2[cH:85][cH:86][cH:87][cH:88][cH:89]2)[c:90]2[cH:91][cH:92][cH:93][cH:94][cH:95]2)[cH:96][cH:97][cH:98][cH:99][cH:100]1>>[c:2]1(-[c:32]2[n:33][cH:34][cH:35][cH:36][cH:37]2)[cH:3][cH:4][c:5]([O:25][CH3:26])[c:6]([C:8](=[O:9])[c:10]2[cH:11][n:12][c:13]([NH:16][c:17]3[c:18]([F:24])[cH:19][c:20]([F:23])[cH:21][cH:22]3)[cH:14][cH:15]2)[cH:7]1
