Dimethylformamide → 1-(2-bromo-4-fluorophenyl)-N-[4-({2-[(cyclopropylcarbonyl)amino]imidazo[1,2-a]pyridin-6-yl}oxy)-3-fluorophenyl]-6-methyl-2-oxo-1,2-dihydropyridine-3-carboxamide

反応式

[Br:25][c:26]1[c:27](-[n:33]2[c:34](=[O:43])[c:35]([C:40](=[O:41])[OH:42])[cH:36][cH:37][c:38]2[CH3:39])[cH:28][cH:29][c:30]([F:32])[cH:31]1.[CH3:77][N:78]([CH3:79])[CH:80]=[O:81].[CH:68]([N:69]([CH2:70][CH3:71])[CH:72]([CH3:73])[CH3:74])([CH3:75])[CH3:76].[NH2:1][c:2]1[cH:3][c:4]([F:24])[c:5]([O:6][c:7]2[cH:8][cH:9][c:10]3[n:11]([cH:12]2)[cH:13][c:14]([NH:16][C:17](=[O:18])[CH:19]2[CH2:20][CH2:21]2)[n:15]3)[cH:22][cH:23]1.[P-:44]([F:45])([F:46])([F:47])([F:48])([F:49])[F:50].[n:51]1([O:52][C:53]([N:54]([CH3:55])[CH3:56])=[N+:57]([CH3:58])[CH3:59])[c:60]2[n:61][cH:62][cH:63][cH:64][c:65]2[n:66][n:67]1>>[NH:1]([c:2]1[cH:3][c:4]([F:24])[c:5]([O:6][c:7]2[cH:8][cH:9][c:10]3[n:11]([cH:12]2)[cH:13][c:14]([NH:16][C:17](=[O:18])[CH:19]2[CH2:20][CH2:21]2)[n:15]3)[cH:22][cH:23]1)[C:40]([c:35]1[c:34](=[O:43])[n:33](-[c:27]2[c:26]([Br:25])[cH:31][c:30]([F:32])[cH:29][cH:28]2)[c:38]([CH3:39])[cH:37][cH:36]1)=[O:41]