3-Amino-1,2-propanediol → N-(2,3-Di(acryloyloxy)propyl)hexahydrophthalimide

HRID 3070

反応式

HRID 3070 の反応式
[NH2:1][CH2:2][CH:3]([OH:6])[CH2:4][OH:5].[C:7]1(=[O:17])[O:12][C:10](=O)[CH:9]2[CH2:13][CH2:14][CH2:15][CH2:16][CH:8]12>C(O)C>[C:10]([O:6][CH:3]([CH2:4][O:5][C:7](=[O:17])[CH:8]=[CH2:16])[CH2:2][N:1]1[C:7](=[O:17])[CH:8]2[CH2:16][CH2:15][CH2:14][CH2:13][CH:9]2[C:10]1=[O:12])(=[O:12])[CH:9]=[CH2:13]

参加物

4

反応物 2

HCID 735613-Amino-1,2-propanediolHCID 85689Hexahydrophthalic anhydride

生成物 1

HCID 18934212N-(2,3-Di(acryloyloxy)propyl)hexahydrophthalimide収率 109.7%

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒

実験手順

A 500-ml, two necked flask was equipped a magnetic stirring bar, heating mantle and condenser. The flask was charged with 46 g of 3-amino-1,2-propanediol (0.50 mol.) and 300 ml of ethanol. Next, 77 g of hexahydrophthalic anhydride (0.50 mol.) was slowly added to the flask after which the reaction was refluxed for 12 hours. The imide formation was confirmed by IR. The ethanol was removed by a rotoevaporator to yield 92 g (81%) of the N-[2,3-di(hydroxy)propyl]hexahydrophthalimide.

後処理

  1. customA 500-ml, two necked flask was equipped a magnetic stirring bar
  2. temperatureheating mantle and condenser
  3. temperaturewas refluxed for 12 hours
  4. customThe ethanol was removed by a rotoevaporator

出典と根拠

ORDレコード
ord-ebb2fd6722bb446b8b566d5f8733e3f7
出典データセット
uspto-grants-1998_03
特許番号
US05733648

関連ノート

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