L-Lactic Acid → (s)-2-Hydroxy-n-[(s)-5-(2-methoxy-ethyl)-6-oxo-6,7-dihydro-5h-dibenzo[b,d]azepin-7-yl]-propionamide
反応式
[NH2:1][C@@H:2]1[C:8](=[O:9])[N:7]([CH2:10][CH2:11][O:12][CH3:13])[C:6]2[CH:14]=[CH:15][CH:16]=[CH:17][C:5]=2[C:4]2[CH:18]=[CH:19][CH:20]=[CH:21][C:3]1=2.[C:22](O)(=[O:26])[C@H:23]([CH3:25])[OH:24]>>[OH:24][C@@H:23]([CH3:25])[C:22]([NH:1][C@@H:2]1[C:8](=[O:9])[N:7]([CH2:10][CH2:11][O:12][CH3:13])[C:6]2[CH:14]=[CH:15][CH:16]=[CH:17][C:5]=2[C:4]2[CH:18]=[CH:19][CH:20]=[CH:21][C:3]1=2)=[O:26]参加物
3
実験手順
Using (S)-7-amino-5-(2-methoxy-ethyl)-5H,7H-dibenzo[b,d]azepin-6-one and L-(+)-lactic acid, the title compound was prepared in the same manner as described for example 5a. Colourless, viscous oil (>98%). MS: m/e=355(M+H+).
出典と根拠
- ORDレコード
- ord-50f42e7a695f4fd2adf0489fbc11d8ea
- 出典データセット
- uspto-grants-2008_09