Dimethylformamide → 2-Oxobutyl benzoate

HRID 31659

反応式

HRID 31659 の反応式
Br[CH2:2][C:3](=[O:6])[CH2:4][CH3:5].[C:7]([O-:15])(=[O:14])[C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1.[Na+].CN(C)C=O>C(OCC)C>[C:7]([O:15][CH2:2][C:3](=[O:6])[CH2:4][CH3:5])(=[O:14])[C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1

参加物

5

反応物 3

HCID 6228DimethylformamideHCID 131561-Bromo-2-butanoneHCID 517055Sodium Benzoate

生成物 1

HCID 157432722-Oxobutyl benzoate

試薬・触媒・溶媒 1

HCID 3283Diethyl Ether溶媒

実験手順

A mixture of 1-bromobutan-2-one (7.2 g, 47.7 mmol), sodium benzoate (7.56 g, 52.4 mmol), and N,N-dimethylformamide (72 ml) was stirred at room temperature for 3 hours and 45 minutes. Diethyl ether was added to the reaction mixture and the mixture was washed with water and a saturated saline solution, dried over magnesium sulfate, and filtrated. The filtrate was concentrated under reduced pressure to obtain the title compound (9.5 g, quantitatively) as a light brown oil.

後処理

  1. washthe mixture was washed with water
  2. dry with materiala saturated saline solution, dried over magnesium sulfate
  3. filtrationfiltrated
  4. concentrationThe filtrate was concentrated under reduced pressure

出典と根拠

ORDレコード
ord-7d7c0015b0cc406bb4bdac4994bc8c15
出典データセット
uspto-grants-2008_09
特許番号
US07425634B2

関連ノート

読み込み中…