Tetrahydrofuran → 3-(3,4-Dimethyl-5-thiazol-2-yl-thiophen-2-yl)-8-(1-ethyl-propyl)-2,6-dimethyl-imidazo[1,2-b]pyridazine

反応式

[Br:1][c:2]1[c:3]([CH3:24])[c:4]([CH3:23])[c:5](-[c:7]2[c:8]([CH3:22])[n:9][c:10]3[n:11]2[n:12][c:13]([CH3:21])[cH:14][c:15]3[CH:16]([CH2:17][CH3:18])[CH2:19][CH3:20])[s:6]1.[Br:35][c:36]1[s:37][cH:38][cH:39][n:40]1.[CH2:25]1[O:26][CH2:27][CH2:28][CH2:29]1.[CH3:30][CH2:31][CH2:32][CH2:33][Li:34].[CH3:41][CH2:42][O:43][C:44]([CH3:45])=[O:46]>>[c:2]1(-[c:36]2[s:37][cH:38][cH:39][n:40]2)[c:3]([CH3:24])[c:4]([CH3:23])[c:5](-[c:7]2[c:8]([CH3:22])[n:9][c:10]3[n:11]2[n:12][c:13]([CH3:21])[cH:14][c:15]3[CH:16]([CH2:17][CH3:18])[CH2:19][CH3:20])[s:6]1